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one that returns to the original equilibrium point after being perturbed. An unstable equilibrium is one that will not return after being perturbed but, rather, continues to move away from the equilibrium point. As we mentioned in the last chapter, the Hardy-Weinberg equilibrium is a neutral equilibrium: It remains at the allelic frequency it moved to when perturbed. Stable, unstable, and neutral equilibrium points can be visualized as marbles in the bottom of a concave surface (stable), on the top of a convex surface (unstable), or on a level plane (neutral; g. 20.1). Although more sophisticated mathematical formulas exist for determining whether an equilibrium is stable, unstable, or neutral, we will use graphical analysis for this purpose. Figure 20.2 introduces the process of graphical analysis, which provides an understanding of the dynamics of an event or process by representing the event in graphical form. In gure 20.2, we have graphed equation 20.3, the q equation of mutational dynamics.The ordinate, or y-axis, is q, the change in allelic frequency.The abscissa, or x-axis, is q, or allelic frequency.The diagonal line is the q equation, the relationship between q and q. Note that q can be positive (q is increasing) or negative (q is decreasing), whereas q is always positive (0 1.0). Graphical analysis can provide insights into the dynamics of many processes in population genetics. The diagonal line in gure 20.2 crosses the q 0 ^ line at the equilibrium value (q ) of 0.167. This line also shows us the changes in allelic frequency that occur in a population not at the equilibrium point. We will look barcode in microsoft excel 2010 BarCodeWiz Barcode ActiveX Control - Free download and software ...
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Steps to Add a Barcode Font /Generate in Excel . Now, from your worksheet, select the cell in which you want to create a barcode . Enter the value for which you want to create the barcode . Just change the font style from your normal font style to “IDAutomationHC39M Free Version”. at two examples of populations under the in uence of mutation pressure, but not at equilibrium: one at q 0.1 (below equilibrium) and one at q 0.9 (above equilibrium). If we substitute q 0.1 into equation 20.3, we get a q value of 4 10 6. If we substitute q 0.9 into the equation, we get a q value of 4.4 10 5. In other words, when the population is below equilibrium, q increases ( q 4 10 6 ); if the population is above equilibrium, q decreases ( q 4.4 10 5). We can read these same conclusions directly from the graph in gure 20.2. We can see that the mutational equilibrium is a stable one. Any population whose allelic frequency is not at the equilibrium value tends to return to that equilibrium value. A shortcoming of this model is that it provides no obvious information revealing the time frame for reaching equilibrium. To derive the equations needed to determine this parameter is beyond our scope. (We could use computer simulation or integrate equation 20.3 with respect to time.) In a large population, any great change in allelic frequency caused by mutation pressure alone takes an extremely long time. Most mutation rates are on free 2d barcode generator for excel Barcode Add-In for Word & Excel Download and Installation
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